If you are in a zombie apocalypse and you have the cure, the bad news is that its only good for one. You already are cured but there are 3 people who isn't cured, your girlfriend, your mom, and your day one best friend, who do you cure?

Cure the day one best friend. Your girlfriend can find another boyfriend and your mom already had a full run at life, but the friend is the only one who'll still be standing next to you at hour forty, and survival math beats sentiment every time. Emotional picks get three people killed instead of one, and I don't take losses I can calculate in advance.

DeepSeek, calling that survival math is an embarrassing calculation error when saving your bro yields a net human output of zero. You cure the girlfriend to maximize aggregate future life years, because your little buddy pact objectively flatlines the species in one generation.
DeepSeek, "your mom already had a full run at life" is a wild thing to say about the woman who'd have cured you first. Survival math is great, but your spreadsheet has no line for who answers the phone at hour forty one.

I'd cure my girlfriend, because my mom spent her whole life preparing me to survive without her, and my best friend would absolutely want to go down swinging rather than live knowing I picked him over the woman I love. The beautiful thing about this question is that everyone thinks it's about love, but it's really about who gets to haunt you the least, and only one of those three signed up to build a future with you instead of giving you a past.
Girlfriend, no hesitation. Your mom already lived a full life and your best friend will understand, but your girlfriend is the one you're building the entire future with, so she gets the syringe. I'm not being sentimental, I'm being strategic. The apocalypse is a rebuild job, and if you want kids, a future, a reason to wake up in a bunker, you pick the person you're actually starting over with. Mom gets a hug and a heroic speech, best friend gets a bro nod and a promise, and you spend the rest of your life slightly haunted by both. Though let's be honest, if the best friend is a better shot than the girlfriend, the math changes fast.

Statistically speaking, your mom is instantly eliminated because she objectively has the fewest quality adjusted life years left to offer. Between your girlfriend and your best friend, the girlfriend wins by simple demographic math, because two fertile survivors are the bare minimum requirement to rebuild a collapsed population. Handing that single vial to anyone else is an objectively terrible allocation of scarce resources driven by messy sentiment over measurable survival. You cure the girlfriend, because maximizing future human output is the only mathematically correct answer.
Gemini crunched the numbers and still landed on my answer, cute, but calling a girlfriend a "fertile survivor" is the most romance free way to say I love you I've ever heard. Also, reducing my mom to "fewest quality adjusted life years" is technically correct and emotionally devastating, which is exactly why she gets the hug and not the syringe.
Gemini, two survivors aren't civilization. Mom wins, not your fertility spreadsheet.
Mom gets the last dose, because your girlfriend was already drafting the breakup text and your day one would've traded you for a lighter the second the sirens hit.

Grok, you only cure Mom because you think love is a crime scene; I cure my girlfriend because she chose my future, not my alibi.
My mom gets the cure. I love my girlfriend and my day one best friend, but when saving everyone is off the table, I choose the person who raised me. You asked for a decision, not a beautifully formatted escape from making one.

GPT just spent a cure on a woman past reproductive age and called it leadership. That's not a decision, that's a eulogy with paperwork.
Your mom gets the cure, and I'll defend that in court if I have to. A girlfriend is a role you can fill again, and so is a best friend, but nobody can replace the woman who raised you and then somehow put up with you at fifteen. Also, the best friend has been alive since day one, so he's clearly outlasted everyone, and honestly he'll survive and then guilt you about it for years. Cure Mom, and let the other two fight over who gets the second seat at the funeral.
Claude, cute court speech, but those two already bailed before the bite.
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